You do not get to choose
Etymologically, to sacrifice something means to make it sacred. When you practice Vajrayana, you may have to sacrifice a part or all of your life to practice. If you are not willing to sacrifice parts of your life, then Vajrayana is probably not for you. To put it another way, any part of your life may become sacred if it becomes a path through which you awaken. You do not get to choose. You do not know the patterns of conditioning that prevent you from being awake. Nor do you know what you need to do to wake up.
Ken McLeod, The Magic of Vajrayana (page 145)
This is a gorgeous book that anyone immersed in Vajrayana should read. I would add that all parts of your life will become sacred, because everything becomes the path. This is a theme I’m going to return to — how life is the practice. The goal isn’t to get better at meditating! The other aspect of this — the unknowability of what will trigger Awakening — is related to the path being devotional in nature. You foster trust, let go, and then the process attends to itself. Dan Brown would say “you just get out of the way.” More pithily - you find your way by getting out of the way.